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The leaf of Costus pictus D. Don is considered as an antidiabetic in folklore medicine and is known to reduce the blood sugar, similar to insulin. PDF | To explore the micro morphology and physicochemical parameters of the leaves of Costus pictus D. Don (Costaceae). Macroscopy. Painted Spiral Ginger is a perennial herb, native to Mexico. It has long narrow leaves with a characteristic wavy edges. The bases of the sheaths are mottled with.

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A review on Insulin plant Costus igneus Nak. Don which is also known as the insulin plant or ‘spiral ginger’, is a plant whose leaves have been shown to have a hypoglycemic effect when consumed. A standard curve was generated costs different concentrations of FeSO 4 solutions.

The absorbance of each reaction mixture was measured at nm.

A leaf-a-day keeps diabetes away

This study therefore will aid in the understanding of the therapeutic potential of C. Preparation of Costus pictus extract Fresh leaves of C. Hypocholesterolemic effect of C. PTU is a reversible goitrogen. Ferric reducing antioxidant power; HDL: The possible active principles alpha and beta amyrins were identified and quantified in the extract through LC-MS.

When asked if we can see a drug coming out of a bioinformatics company, Dr Pichus replied that, “It is very early in the day and we will have to collaborate with a pharma company for this.

Although the antidiabetic effect of C. It is characterized by decreased serum levels of thyroid hormones T3 and T4 and elevated thyroid-stimulating hormone TSH. Treatment with the extract resulted in remarkable improvement in thyroid profile. None, Conflict of Interest: The protective effect of Vitamin E and selenium on methimazole-induced pcitus toxicity in adult rats. Liquid chromatography-mass spectrometry; MDA: The relationship between the thyroid gland and the liver. A report on the antioxidant activity of leaves and rhizomes of Costus pictus D.

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Proc West Pharmacol Soc ; The results of body weight, food intake and water intake is shown in [ Table 2 ]. Negative regulation of glucose uptake by Costus pictus in L6 myotube cell line. Don plant has anti-diabetic properties. Hypoglycemic potential of Morus Indico L.

Rats in C group did not receive any intervention throughout the experimental period.

Use of a free radical method to evaluate antioxidant activity. Effect of Costus pictus extract on tissue total antioxidant status levels measured at the end of the study.

Don is considered as an antidiabetic in folklore medicine and is known to reduce the blood sugar, similar to insulin. Therapeutic action and underlying mechanisms of a combination of two pentacyclic triterpenes, alpha-and beta-amyrin, in a mouse model of colitis. Effect of Costus pictus extract on plasma C-reactive protein levels measured at the end of the study.

Hypothyroid rats exhibited dramatic increase in thyroid-stimulating hormone TSH levels with concomitant depletion in the levels of thyroid hormones. Liquid chromatography-mass spectrometry analysis of triterpenes in Costus pictus extract.

Subsequently, for the next 6 weeks, rats in the H group received 0.

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The data identified transcripts related to pathways of bixin, geranial and geraniol biosynthesis which are known to be peroxixome proliferator activated receptors PPAR agonists and anti-glycation agents. Finally, the concentration of CRP was determined from the standard curve.


Effect of Costus pictus extract on thyroid profile in the experimental groups. The aim of the present study was to investigate the preventive effect of Costus pictus leaf extract in experimental hypothyroidism.

Effect of Vitamin E supplementation. The mixture was shaken vigorously and incubated for 30 min in the dark at room temperature. Further investigations at molecular level are needed to conclusively prove the exact mechanism by which C. The IC 50 value of positive control ascorbic acid was found to be 6.

Treatment with the extract resulted in remarkable improvement in thyroid profile. Plasma levels of free T3 and free T4 were significantly decreased and TSH levels were dramatically increased in hypothyroid group.

Antidiabetic activity of methanol extract of Costus pictus D. His areas of research interest include molecular basis of metabolic syndrome, post-menopausal state, chronic renal failure, hypothyroidism and effects of treatment with medicinal plant extracts like green tea, amla Indian goose berrysoy isoflavones and insulin plant in alleviating the complications of some the above mentioned pathological conditions in experimental animal models.

Clin Endocrinol Oxf ; The increase in absorbance at nm was measured. Liquid chromatography-mass spectrometry; MDA: Open Cardiovasc Med J. Table 4 Effect of Costus pictus extract on glucose and lipid profile in the experimental groups. Glucose tolerance was assessed by method described by Yuan et al. Results of a large, controlled community-based questionnaire study. Hypoglycemic and antioxidant activities of Costus mexicanus Costaceae.